TY - CHAP T1 - Urinary tract infection in spina bifida T2 - Urogenital Infections and Inflammations AU - Rawashdeh, Yazan F. AU - Hvistendahl, Gitte M. ED - Naber, Kurt G. AD - Yazan F. Rawashdeh, Aarhus University Hospital, Paediatric Urology Section, Department of Urology, -, -, Denmark, Phone: -, E-mail: yazan@clin.au.dk N2 - The urological consequences of spina bifida in children remain challenging for the paediatric urologist and nephrologist. And as the majority of these patients are born with normal urinary tracts and renal function the mainstay of modern management has been to preserve renal function by countering the effects of high bladder pressures, detrusor sphincter dyssynergia and urinary tract infection (UTI) by clean intermittent catheterization (CIC), combined with administering anticholinergics and at times prophylactic antibiotics. Solid evidence derived from well-designed clinical trials for such management protocols are sparse and patently in need of revision and empirical confirmation. Reviewing MEDLINE and The Cochrane Library for English language studies dealing with UTI in paediatric spina bifida over the last decade resulted in 47 hits which were subsequently reviewed shortlisting 22 publications of sufficient relevance and quality for final analysis. Despite the heterogeneous nature of results data indicate that CIC remains a cardinal aspect of management and that regardless of catheter type (single use vs. reusable) no increase in UTI rates were detectable. Furthermore, studies confirm that use of prophylactic antibiotics in paediatric spina bifida patients is superfluous and can safely be discontinued at minimal risk. PY - 2018 DA - 2018/11/02 DO - 10.5680/lhuii000043 LA - en L1 - https://books.publisso.de/en/system/getFile/152 UR - https://dx.doi.org/10.5680/lhuii000043 L2 - https://dx.doi.org/10.5680/lhuii000043 PB - German Medical Science GMS Publishing House CY - Berlin ER -