TY - CHAP T1 - Urinary microbiota analyzed by extended microbiology in subjects with and without urological disorders T2 - Urogenital Infections and Inflammations AU - Naboka, Yulia AU - Kogan, Michael ED - Naber, Kurt G. AD - Prof. Michael KOGAN M.D., PhD, Rostov State Medical University, Department of Urology, Nakhichevanskiy st. 29, 344022, Rostov-on-Don, Russia, Phone: +7 (863) 201-44-48, E-mail: dept_kogan@mail.ru N2 - A healthy person’s urine is not a sterile environment, and its microbiota contain a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, with Gram-positive aerobic microorganisms predominating. There are significant differences between the urinary microbiota of healthy men and women. The composition of healthy women’s urinary microbiota depends on age and sexual activity. Non-clostridial anaerobic bacteria (NAB) predominate Enterobacteriaceae in case of acute obstructive pyelonephritis with bacteriuria of 104 CFU/ml and higher. Experiments have shown that obstructive pyelonephritis can be caused by various species of NAB (Peptococcus spp., Bacteroides spp., Eubacterium spp.). In every third case of recurrent symptomatic uncomplicated lower urinary tract infection (UTI) Enterobacteriaceae with low level bacteriuria of ≤103 CFU/ml are found and every third case of acute cystitis is not associated with typical uropathogens. Low levels of bacteriuria (102–103 CFU/ml) correlate with symptoms of upper and lower UTI and thus cannot be considered contamination. Asymptomatic bacteriuria is normal in healthy individuals. PY - 2018 DA - 2018/03/15 DO - 10.5680/lhuii000021 LA - en L1 - https://books.publisso.de/en/system/getFile/45 UR - https://dx.doi.org/10.5680/lhuii000021 L2 - https://dx.doi.org/10.5680/lhuii000021 KW - urinary tract infection KW - bacteriuria KW - urinary microbiota KW - urine culture KW - urine examination KW - culture medium KW - complicated urinary tract infection KW - uncompli-cated urinary tract infection PB - German Medical Science GMS Publishing House CY - Duesseldorf ER -