TY  - CHAP
T1  - Sex and other host factors influencing urinary tract infection pathogenesis
T2  - Urogenital Infections and Inflammations
AU  - Olson, Patrick D.
AU  - Hunstad, David
ED  - Naber, Kurt G.
AD  - David Hunstad, Washington University School of Medicine, Pediatrics / Molecular Microbiology, 660 S. Euclid Ave., CB 8208, 63110, St. Louis, United States, Phone: +1 314 286 2710, E-mail: dhunstad@wustl.edu
N2  - Biological sex represents the most important host factor that influences urinary tract infections (UTIs), which are most commonly caused by uropathogenic Escherichia coli (UPEC). UTI susceptibility varies by sex and age throughout the patient lifespan, although the disease disproportionally afflicts women throughout the middle ages. Substantial male patient populations are also affected, and morbidity in complicated UTI is higher in men. This review highlights sex-related discrepancies in the disease, and how sex may influence the pathogenesis, outcomes, and treatment of ascending UTI.
PY  - 2018
DA  - 2018/02/16
DO  - 10.5680/lhuii000016
LA  - en
L1  - https://books.publisso.de/en/system/getFile/120
UR  - https://dx.doi.org/10.5680/lhuii000016
L2  - https://dx.doi.org/10.5680/lhuii000016
KW  - urinary tract infection
KW  - sex differences
KW  - androgens
KW  - testosterone
KW  - estrogen
KW  - pyelonephritis
KW  - cystitis
KW  - renal abscess
PB  - German Medical Science GMS Publishing House
CY  - Duesseldorf
ER  -