TY  - CHAP
T1  - Roles of the vagina and the vaginal microbiota in urinary tract infection: evidence from clinical correlations and experimental models
T2  - Urogenital Infections and Inflammations. Living Handbook
AU  - Lewis, Amanda
AU  - Gilbert, Nicole
ED  - Naber, Kurt G.
ED  - Bjerklund Johansen, Truls Erik
AD  - Dr. Amanda Lewis, Washington University School of Medicine in Saint Louis, Molecular Microbiology, 425 S Euclid Ave, 63110, Saint Louis, United States, E-mail: mandylew@gmail.com; Dr. Nicole Gilbert, Washington University School of Medicine in Saint Louis, Obstetrics and Gynecology, 425 S Euclid Ave, 63110, Saint Louis, United States, E-mail: gilbert@wustl.edu
N2  - Mounting evidence indicates that the vagina can harbor uropathogenic bacteria. Here, we consider three roles played by the vagina and its bacterial inhabitants in urinary tract infection (UTI) and urinary health. First, the vagina can serve as a reservoir for Escherichia coli, the most common cause of UTI, and other recognized uropathogens. Second, several vaginal bacterial species are frequently detected upon urine culture but are underappreciated as uropathogens, and other vaginal species are likely under-reported because of their fastidious nature. Third, some vaginal bacteria that are not widely viewed as uropathogens can transit briefly in the urinary tract, cause injury or immunomodulation, and shift the balance of host-pathogen interactions to influence the outcomes of uropathogenesis. This chapter describes the current literature in these three areas and summarizes the impact of the vaginal microbiota on susceptibility to UTI and other urologic conditions. Test 
PY  - 2021
DA  - 2021/06/23
DO  - 10.5680/lhuii000055
LA  - en
L1  - https://books.publisso.de/en/system/getFile/80711
UR  - https://dx.doi.org/10.5680/lhuii000055
L2  - https://dx.doi.org/10.5680/lhuii000055
KW  - Bacterial vaginosis
KW  - uropathogen
KW  - Escherichia coli
KW  - Gardnerella vaginalis
KW  - Group B Streptococcus
KW  - Lactobacillus
KW  - Aerococcus
KW  - Staphylococcus
KW  - Ureaplasma
KW  - lower urinary tract symptoms
KW  - probiotic
PB  - German Medical Science GMS Publishing House
CY  - Berlin
ER  -