TY  - CHAP
T1  - Prevention of prematurity by early diagnosis and treatment of bacterial urogenital infections – The role of bacterial vaginosis
T2  - Urogenital Infections and Inflammations
AU  - Hoyme, Udo B.
ED  - Naber, Kurt G.
AD  - Udo B. Hoyme, HELIOS Hospital Erfurt Ltd., Department of Gynecology and Obstetrics, Reichartstraße 10, Erfurt, Deutschland, Phone: -, E-mail: hoymej@aol.com
N2  - Bacterial vaginosis has a significant relative risk for miscarriage or prematurity of 1.4–6.9%. In the initial Erfurt trial 0.3% of the neonates with gestational age <32 + 0 weeks were seen in an intervention group vs. 3.3% (p <.01) in the control group; in the Thuringia campaign the figures were 0.94% vs. 1.36% (p <.01) for the entire state. The rate of newborns <1,000 g was reduced to 0.38%, the lowest incidence ever seen in any of the German states in the past. The Erfurt and Thuringia programmes represent a preventional prospective, controlled study. This should count even more, as there was no success in reducing the rate of underweight children either on federal state or national level in the decades preceding the study.  However, after discontinuation of the campaign the prematurity rates in Thuringia monitored till 2005 are as high as prior to our statewide programme in general as for our hospital in particular. Now, following correction, detailed analysis and extensive discussion of the data a model trial of four health insurance providers in five German states was initiated, aimed at scientific evaluation as well as cost-benefit analysis. The preliminary new data and calculations also signal substantial savings as well as implementation of new simplified pH-measurement techniques and tools. Prevention of prematurity by screening, diagnosis and therapy of genital infections is without any doubt a step for optimising and rationalising the health care system. Also the noncommensurable extraordinary strain on all parties involved could be reduced in a most beneficial way. Similar developments take place abroad: the described innovative pH measurement regime is introduced in more than 20 countries so far. 
PY  - 2019
DA  - 2019/02/28
DO  - 10.5680/lhuii000009
LA  - en
L1  - https://books.publisso.de/de/system/getFile/225
UR  - https://dx.doi.org/10.5680/lhuii000009
L2  - https://dx.doi.org/10.5680/lhuii000009
KW  - bacterial vaginosis
KW  - prevention of prematurity
KW  - intravaginal pH-screening
PB  - German Medical Science GMS Publishing House
CY  - Berlin
ER  -