TY - CHAP T1 - Etiology of chronic prostatitis/chronic pelvic pain syndrome – How animal models guide understanding of the syndrome T2 - Urogenital Infections and Inflammations AU - Murphy, Stephen F. AU - Thumbikat, Praveen ED - Naber, Kurt G. AD - Praveen Thumbikat, Department of Urology, Chicago, Vereinigte Staaten, E-mail: thumbikat@northwestern.edu N2 - There remains a limited understanding of the etiology of CPPS. Given the diffuse nature of the symptoms and the heterogeneous nature of the patient population this is not surprising. Of the information that exists it is possible that further subdividing the patient population based on certain inflammatory criteria might be useful in basic research on CPPS going forward. Our laboratory and others have begun to understand and regard CPPS as an underlying autoimmune defect that is exacerbated by damage to the prostate resulting in a chronic symptomology. Much of this robust information on the emergence of CPPS has come from research performed in murine models of the disease. PY - 2018 DA - 2018/05/17 DO - 10.5680/lhuii000026 LA - en L1 - https://books.publisso.de/de/system/getFile/35 UR - https://dx.doi.org/10.5680/lhuii000026 L2 - https://dx.doi.org/10.5680/lhuii000026 PB - German Medical Science GMS Publishing House CY - Berlin ER -